C-Reactive Protein (CRP)
C-Reactive Protein (CRP) is an acute-phase protein, produced only in the liver.
| Product Specifications | |
|---|---|
| Source | Human Fluids |
| Form | Liquid |
| Buffer | TRIS buffer containing Sodium Azide and NaCl at pH 7.0 |
| Concentratoin | 1-5 mg/mL |
| Purity | Immunopure is ≥ 95% by SDS Page, Single band at ~23kDA |
| Assay | Assay performed on Roche Cobas c501 |
| Storage | 2-8°C |
| Molecular Weight | 115 kDa |
| Appearance | Clear, colorless to faint yellow |
The concentration of CRP in plasma or scrum increases significantly in the presence of infectious and noninfenctious inflammation, tissue damage, and malignant tumors. The protein is also present in the active stages of inflammatory disorders like rheumatoid arthritis, ankylosing spondylitis, Reiter’s syndrome, and psoriatic anthropathy, systemic lupus erythematosus, polyarteritis, ulceratic colitis, and Crohn’s disease. CRP is used in many parts of the world as a screening test when a patient is admitted to the ER or hospital. CR is pentameric serum protein with an approximate molecular weight of 115 kDa and is composed of five non-covalently linked identical subunits each with a molecular weight of 23 kDa.
